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Systemic Sclerosis Microenvironment Dysregulates Endothelial Progenitor Cell Migration and Tubulogenic Ability and Contributes to Vasculopathy

Dr. Pravin Hissaria - Division of Human Immunology, SA Pathology

The aim of this study is to determine whether the endothelial progenitor cells from patients with early active SSc behave differently from normal cells and whether there are factors in the serum of patients with SSc which may be responsible for this abnormal behaviour. The altered behaviour of these cells in patients with SSc is poorly understood, based on limited studies to date, but this would be a prime target for therapeutic intervention in these serious complications of SSc.

 

Dr. Pravin Hissaria is currently Immunology Staff Specialist at SA Pathology/IMVS/RAJ and Translational Clinical research Laboratory Head, Human Immunology.

Over the past five years, she has received numerous awards and academic achievements including the Eddie Hirst Prize in 2005 for highest marks obtained by an Australian candidate in basic pathological  sciences examination which was awarded by the Royal College of Pathologists of Australia.